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P38 MITOGEN-ACTIVATED PROTEIN KINASES
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DeCS
Descriptor
English
:
p38 Mitogen-Activated Protein Kinases
Descriptor
Spanish
:
Proteinas Quinasas p38 Activadas por Mitógenos
Descriptor
Portuguese
:
Proteínas Quinases p38 Ativadas por Mitógeno
Synonyms
English
:
Mitogen-Activated Protein Kinase p38
Tree Number:
D08.811.913.696.620.682.700.567.878
D08.811.913.696.620.682.700.646.750.843
D12.644.360.450.835
D12.776.476.450.835
Definition
English
:
A mitogen-activated protein kinase subfamily that regulates a variety of cellular processes including
CELL GROWTH PROCESSES
;
CELL DIFFERENTIATION
;
APOPTOSIS
; and cellular responses to
INFLAMMATION
. The P38 MAP kinases are regulated by CYTOKINE RECEPTORS and can be activated in response to bacterial pathogens.
History Note
English
:
2005(1994)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
38735
Unique Identifier:
D048051
Occurrence in VHL
:
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CID-10
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